Tony Shalhoub of "Monk" would be cool, considering his character on that show! They could put him and Howie on during the same season, and have them both wear gloves! HA. Probably would be tough for BOTH of them with prime time series...
How about bringing back some Nick at Nite characters? The ones who have grown up, and make a whole season about grown-up kid stars-that would be fun! Like Marsha from the Brady Bunch, Tony Dow from the Beaver, Susan Dey or David Cassidy from The Partriges, etc. THAT would be a really cool show-they'd all be around the same age, if my calculations are right. Not the parents, just the kids!
Last I saw most of them, they were all in a support group for 'Kids who grew up in Hollywood', you know that group headed by Paul Peterson, of the Donna Reed Show? Just a thought...